Sildenafil Citrate, purchased as Viagra and under a number of other trade names from genuine online pharmacies, is a medication used to deal with ED and pulmonary arterial hypertension (PAH).Viagra can be used to deal with ED, the inability to get and/or maintain an erection of the male member that is adequate for sexual sex.
At the start of 2000, Viagra sales accounted for 92 percent of the world sell for doctor given ED pills. Up to 2007, Viagra ’s global share had plummeted to about 50 percent because of numerous factors, not excluding the entry of Cialis and Levitra, accompanied by numerous other counterfeits and clones, and reports of vision loss in people taking PDE5 inhibitors.
Sildenafil Citrate is metabolized by liver enzymes and excreted by both the liver and kidneys. If taken with a high-fat meal, absorption is reduced; the time was taken to reach the maximum plasma concentration increases to up to one hour, and the maximum concentration itself is decreased by nearly one-third.
Recommendations are given to men with kidney or liver impairments, and men over age 65, start at the lowest possible dosage of Viagra (25 mg). Clinical studies show that the medication builds up in the plasma of these patients to a concentration that is up to eight times higher than normal. Caution is also recommended in prescribing the medication to individuals with retinitis pigtosa, an unusual genetic eye disorder. Viagra might not be taken more than once per day by anyone.
Viagra in some circumstances can also interact with other prescription and over-the-counter (OTC) medicines, either increase or decrease the intended therapeutic effects of one or both medications. Some medications that have a known interaction with Viagra include the protease inhibitor ritonavir and the antibiotic erythromycin. For this reason, it is critical that men who are given Viagra let their healthcare givers know all the medicines they are taking.
Males who are taking Viagra and inadvertently or intentionally take a medication containing nitrates in some circumstances can are suffering from life-threatening hypotension-a severe drop in blood pressure